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METABOLEX RAISES $4 MILLION IN SECOND CLOSE OF PRIVATE FINANCING FOR TOTAL FUNDING OF $31 MILLION

HAYWARD, CA (January 12, 2004): Metabolex, Inc., a privately held pharmaceutical firm that discovers and develops drugs to treat diabetes and related metabolic diseases, today announced that it has raised an additional $4 million in a second close of its recent private equity financing. This close brings the total raised by Metabolex in this sixth round of funding to $31 million. The company originally announced a first close of this venture financing for $27 million on August 27, 2003. Participants in the second close included Birchmere Ventures, Merlin Biomed Group and CIBC World Markets. CIBC World Markets was the agent for this financing.
“We are very pleased to receive this additional funding from these prominent and experienced life sciences investors,” said Harold Van Wart, Ph.D., Metabolex president and chief executive officer. “Their participation further underscores the important investment opportunity that Metabolex offers as a discoverer and developer of novel drugs to treat diabetes, one of the fastest growing health care problems in the developed world.”
About Metabolex
Metabolex, Inc. is a privately held pharmaceutical company dedicated to the discovery and development of drugs to treat diabetes and related metabolic disorders. The company’s lead compound, metaglidasen, is a novel insulin sensitizer in Phase I-II clinical development. Metabolex has also built a portfolio of other potential diabetes therapeutics, which includes a product candidate in preclinical development and various programs optimizing lead drug candidates. Additionally, Metabolex has two target discovery programs that have produced one of the world’s largest databases of diabetes-expressed genes. One of these programs, in insulin secretion, is partnered with Pfizer. The other, in insulin resistance, is partnered with Astellas Pharma Inc.
Contacts: For Media:
Mark Bagnall
Metabolex Senior Vice President
Chief Finance and Operations Officer
(510) 293-8800
Joan Kureczka (415) 821-2413
Kureczka/Martin Associates
Jkureczka@aol.com